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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4579 | Pentagastrin | ICI-50123 | Others , cholecystokinin |
Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins. | |||
T24821 | Spizofurone | Espizofurona,AG-629 | Others |
Spizofurone (Espizofurona) has antiulcer activity, protective effect on the gastric mucosa of rats, and can increase alkaline secretion in isolated bullfrog duodenal mucosa. | |||
T15005 | CP-66948 | Histamine Receptor | |
CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa. | |||
T31675 | Esaprazole | C/63 | Others |
Esaprazole (C/63) has a dose - dependent cellular protective effect on the human gastric mucosa. | |||
T1562 | Rebamipide | Proamipide,OPC12759 | Free radical scavengers , COX , Prostaglandin Receptor |
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ... | |||
T34087 | Plaunotol | Kelnac,Plaunotolum | |
Plaunotol is a gastric protective agent that increases prostaglandins in the gastric mucosa and accelerates ulcer healing. | |||
T31958 | Glycine-pentagastrin | Glycine pentagastrin,Boc-gly-trp-met-asp-phe-NH2,Tbgtmap | |
Glycine-pentagastrin can enhance gastric mucosal defence mechanisms against acid and protect the gastric mucosa from experimental injury. | |||
T39795 | Tricarbonyldichlororuthenium(II) dimer | CORM-2 | |
Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and ... | |||
T28335 | PD 140376 | PD-140376,PD140376 | |
PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig gastric mucosa & cerebral cortex in the peripheral and central nervous systems. | |||
TP1838 | Xenin | ||
Xenin is a 25 amino acid peptide that has been identified in human gastric mucosa in the search for a counterpart to the amphibian octapeptide xenopsin. | |||
T71801 | Arbaprostil | ||
Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inh... | |||
T81074 | Sucrose octasulfate sodium | ||
Sucrose octasulfate, a constituent of sulfoaluminum, promotes the release of somatostatin-like immunoreactivity (SLI) through direct interaction with D cells within the gastric mucosa, thereby exerting its ulcer-healing ... | |||
T21939 | ATB-337 | ||
S-Diclofenac is a novel NSAID formed by linking diclofenac to an H2S-releasing moiety. S-Diclofenac spares the gastric mucosa of injury despite markedly suppressing prostaglandin synthesis [1]. | |||
TN4489 | Manassantin A | ERK , cAMP , TNF , NF-κB , MAPK , COX , HIF , Prostaglandin Receptor , JNK , STAT | |
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibitio... | |||
T38045 | Cholesterol β-D-Glucoside | ||
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose . It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It activates heat shock transcription factor 1 (Hsf1) in respons... |